Deoxycorticosterone pivalate (DOCP), also known as desoxycorticosterone trimethyl acetate (DOC-TMA or DCT) and sold under the brand names Zycortal, Percorten V, and Percorten M, is a

mineralocorticoid Mineralocorticoids are a class of corticosteroids, which in turn are a class of steroid hormones. Mineralocorticoids are produced in the adrenal cortex and influence salt and water balances (electrolyte balance and fluid balance). The primary mi ...

medication and a

mineralocorticoid ester This is a list of corticosteroid esters, including esters of steroidal glucocorticoids and mineralocorticoids. Esters of natural corticosteroids Desoxycortone esters * Desoxycortone acetate (deoxycortone acetate; desoxycorticosterone acetat ...

. It is formulated as a

microcrystalline A microcrystalline material is a crystallized substance or rock that contains small crystals visible only through microscopic examination. There is little agreement on the range of crystal sizes that should be regarded as microcrystalline, but the ...

aqueous suspension In chemistry, a suspension is a Mixture#Homogeneous and heterogeneous mixtures, heterogeneous mixture of a fluid that contains solid particles sufficiently large for sedimentation. The particles may be macroscopic, visible to the naked eye, usual ...

, is administered by

intramuscular injection Intramuscular injection, often abbreviated IM, is the injection of a substance into a muscle. In medicine, it is one of several methods for parenteral administration of medications. Intramuscular injection may be preferred because muscles have ...

at regular intervals, and has a prolonged

duration of action Pharmacodynamics (PD) is the study of the biochemical and physiologic effects of drugs (especially pharmaceutical drugs). The effects can include those manifested within animals (including humans), microorganisms, or combinations of organisms (for ...

. The medication is the C21 pivalate (trimethylacetate)

ester In chemistry, an ester is a compound derived from an oxoacid (organic or inorganic) in which at least one hydroxyl group () is replaced by an alkoxy group (), as in the substitution reaction of a carboxylic acid and an alcohol. Glycerides ar ...

11-deoxycorticosterone 11-Deoxycorticosterone (DOC), or simply deoxycorticosterone, also known as 21-hydroxyprogesterone, as well as desoxycortone (INN), deoxycortone, and cortexone, is a steroid hormone produced by the adrenal gland that possesses mineralocorticoid ac ...

References

Corticosteroid esters Diketones Mineralocorticoids Pivalate esters Pregnanes Prodrugs Progestogens Veterinary drugs {{Steroid-stub

See also

References